An Oral Disease Severity Score for pemphigus vulgaris
نویسندگان
چکیده
منابع مشابه
Prosthodontic Rehabilitation of an Oral Pemphigus Vulgaris Patient
Phemphigus is a serious autoimmune disease characterized by acantholysis and subsequent blistering of the skin and oral mucosa, mediated by autoantibodies directed against intercellular antigens desmoglein-3 and desmoglein-1.1-3 There are three immunologic forms of pemphigus; pemphigus foliaceus, pemphigus vulgaris (PV) and paraneoplastic pemphigus.4 PV accounts for 70 of the cases.5 The diseas...
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Unit of Histology and Embryology, Department of Basic Biomedical Sciences, Faculty of Health Sciences, University of Talca, Talca, Chile, Department of Oral Diagnosis, School of Dentistry, State University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil, Mass Spectrometry Laboratory, Brazilian Biosciences National Laboratory CNPEM, Campinas, São Paulo, Brazil, Unit of Oral Pathology, Depar...
متن کاملPemphigus vulgaris activity score and assessment of convergent validity.
Pemphigus is a rare autoimmune blistering disease with different phenotypes. The evaluation of therapeutic interventions requires a reliable, valid and feasible to use measurement. However, there is no gold standard to measure the disease activity in clinical trials. In this study we aimed to introduce the pemphigus vulgaris activity score (PVAS) measurement and to assess the convergent validit...
متن کاملPemphigus Vulgaris and Pemphigus Foliaceus
The word “pemphigus” is derived from the Greek term "pemphix” meaning bubble or blister. Pemphigus is a group of autoimmune diseases (see Table 4) characterized by intra-epithelial blistering, resulting in superficial vesicles or bullae that easily rupture, resulting in ulceration of mucosal and/or cutaneous sites. Although rare, pemphigus causes significant morbidity and potential mortality fo...
متن کاملDesmoglein ELISA in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris.
Anti-desmoglein 3 and 1 autoantibodies are involved in the pathogenesis of pemphigus diseases. Our objective was to assess the value of ELISA in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris. Based on clinical presentation and histopathologic confirmation for the diagnosis of the pemphigus, 38 patients took part in the study. Sera of the patients were te...
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ژورنال
عنوان ژورنال: British Journal of Dermatology
سال: 2018
ISSN: 0007-0963
DOI: 10.1111/bjd.17160